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May 5, 1962

AMYOTROPHY AND HERPES ZOSTER

JAMA. 1962;180(5):405. doi:10.1001/jama.1962.03050180051013
Abstract

The term "shingles" usually brings to mind the cutaneous changes of herpes zoster and the associated radicular pain. It should be borne in mind, however, that muscle paralysis may appear prior to, simultaneously with, or following the cutaneous eruption when the myotome corresponding to an affected dermatome is involved.

It is indeed surprising that the motor phenomena of herpes zoster are not more commonly encountered in clinical practice. According to Denny-Brown,1 some of the pathologic events in herpes zoster include a "poliomyelitis which closely resembles anterior poliomyelitis but is readily distinguished by its unilaterality, segmental localization, and greater involvement of the posterior horn, posterior root and dorsal spinal ganglion" and "true peripheral mononeuritis, seen not only in the nerves distal to the ganglion, but in the anterior nerve root, both within the meninges and in the portion contiguous to the involved spinal ganglion." Greenfield2 asserts that the inflammation

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