[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Other Articles
May 12, 1962

Cyclic Changes in T Waves

Author Affiliations


From the Edward B. Robinette Foundation, Medical Clinic, Hospital of the University of Pennsylvania.

JAMA. 1962;180(6):460-462. doi:10.1001/jama.1962.03050190022004

The T waves of the electrocardiogram are sometimes altered in the absence of heart disease, but the author has not found any reports of T wave changes occurring cyclically in association with the menstrual period. In the present case the T wave changes occurred in the intermenstrual periods. The changes suggested myocardial ischemia, but there was no associated pain, dyspnea, or other evidence of heart disease. Following a supravaginal hysterectomy and bilateral salpingoovariectomy because of a large uterine fibroid, electrocardiograms made twice weekly for 10 months and once weekly for 6 months thereafter have been normal. The time relationship suggested that the electrocardiographic changes were apparently associated with some intermenstrual process, but efforts to reproduce the T wave changes by hormone treatment were not successful.