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May 26, 1962


JAMA. 1962;180(8):687. doi:10.1001/jama.1962.03050210049014

Although skin tests of various kinds have long L been used in the diagnosis of allergies, the results are not always consistent, and both false negative and false positive results have been observed. Curran and Goldman1 have attempted to resolve this paradox by a series of skin tests on 3 groups of subjects. Group 1 consisted of persons in whom no personal or family history of allergy could be elicited by careful questioning. A few of these had to be dropped because they later remembered possible allergic experiences. It was observed that even careful questioning has not always resulted in the exclusion of allergy.

Group 2 consisted of persons with a personal history of hay fever or asthma and Group 3 of persons with a family history but no personal history of allergy. In all 3 groups scratch tests with a surgical needle were made with several extracts and