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June 2, 1962

General Pathology Based on Lectures Delivered at the Sir William Dunn School of Pathology, University of Oxford

JAMA. 1962;180(9):794. doi:10.1001/jama.1962.03050220086021

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The modern science of pathology was born in 1858 when Rudolf Virchow published his Cellular Pathologie. From this date to the early '20's of the present century, the multiple contributions to pathology have been mainly in the field of morphology; the last and most important event in that field being the advent of electron microscopy. However, in the last 25 years other facets in pathology are being highlighted. Great impetus is given to the biochemical, enzymatic, and functional aspects of the body tissues. Actually a third dimension is added to pathology with cellular microchemistry, investigation of enzyme systems, immune reactions, radiation effects, tissue transplantation phenomena, and allergic manifestations.

Sir Howard Florey's book on general pathology must be appraised against this background. This text is a compilation of lectures that have been delivered to the Oxford University medical students who are enrolled in the Honour School of Physiology, where a good

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