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June 16, 1962

Fundamentals of Acid-Base Regulation

JAMA. 1962;180(11):989. doi:10.1001/jama.1962.03050240085030

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Dr. James R. Robinson, a physiologist at the University of Otago Medical School in New Zealand, has written a small book entitled, Fundamentals of Acid-Base Regulation, the purpose of which "is to help the preclinical student and the interested clinician." It should do just that. The author has 2 primary objectives: (1) to describe the constituents of body fluids which contribute to their acid-base balance in terms of current chemical definitions (the so-called Brönsted concept), and (2) to describe the roles of the lungs, the kidneys, and the body's buffer systems in regulating this acid-base balance.

Without attempting to be an exhaustive treatment of the subject, the author has achieved his objectives very satisfactorily. For those who wish to delve more deeply into the problem, a selected and representative bibliography is included. One might have wished that wider use had been made of graphical representations of specific data in many

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