During surgical pneumothorax operations, measurements were made of the oxygen saturation, pH, and pCO2 of the arterial blood in 32 patients, and the circulatory effect of collapse of the operated lung was observed by determining these 3 quantities. The values obtained indicated that, in patients with minimal or moderate unilateral disease, the total collapse of the operated lung was followed by diversion of the blood flow to the unoperated side. In patients with extensive disease of the operated lung, the absence of change in the 3 variables indicated a preexisting diversion of the blood from the diseased lung. In patients with severe bilateral disease, the data indicated a minimal diversion of the blood.
Bonica JJ, Green HD, Takamura JH, Goodson DN, Ziegler TQ, Wilson JF. Factors Which Affect Ventilatory Function During Surgical Pneumothorax. JAMA. 1962;180(3):185–189. doi:10.1001/jama.1962.03050160001001
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