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June 9, 1962

Hyperparathyroidism and Pancreatitis

Author Affiliations

Philadelphia

From the Medical and Surgical Services, Misericordia Hospital (Drs. Turchi, Flandreau, Forte, French), and the Department of Medicine, Hospital of the University of Pennsylvania (Dr. Ludwig).

JAMA. 1962;180(10):799-804. doi:10.1001/jama.1962.03050230001001
Abstract

This paper supports the hypothesis that the concomitance of hyperparathyroidism and pancreatitis is more than coincidental, and that there is some etiologic relationship between the 2 conditions. Study of a patient described in detail in this report and of 26 other patients mentioned in the literature suggests that some cases of pancreatitis are secondary to hyperparathyroidism. The importance of pancreatitis as a diagnostic clue to hyperparathyroidism is emphasized by the increasing number of cases that are being found. The presence of hyperparathyroidism may be obscured by having an otherwise elevated serum calcium concentration reduced to normal by acute pancreatitis. Conversely, when the serum calcium concentration is paradoxically high, or the serum phosphate concentration is low in the presence of acute pancreatitis, appropriate studies to exclude hyperparathyroidism should be performed.

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