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July 11, 2012

Influenza Pandemics—Pregnancy, Pathogenesis, and Perinatal Outcomes

Author Affiliations

Author Affiliations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (Dr Steinhoff); and Dalhousie University, Halifax, Nova Scotia, Canada (Dr MacDonald).

JAMA. 2012;308(2):184-185. doi:10.1001/jama.2012.7911

Since the 1918 influenza pandemic, it has been clear that pandemic influenza is associated with increased morbidity and mortality in pregnancy, and more recent studies have shown that nonpandemic seasonal influenza strains also lead to morbidity for pregnant women and their infants.1 In the 2009 worldwide pandemic of influenza A(H1N1)pdm09, pregnant women were at high risk for severe complications, including death and intensive care unit admission.2