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July 18, 2012

Retinal Detachment and Fluoroquinolones

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Washington University School of Medicine, St Louis, Missouri (Dr Rao; raor@vision.wustl.edu); and University of Iowa Hospitals and Clinics, Iowa City (Dr Dlouhy).

JAMA. 2012;308(3):233. doi:10.1001/jama.2012.6628

To the Editor: Dr Etminan and colleagues1 conducted a case-control analysis of the association of oral fluoroquinolone use with retinal detachment. Understanding the mechanism by which fluoroquinolones may increase retinal detachment risk is important, especially if topical fluoroquinolones, the most common class used during the perioperative period of cataract surgery2 and for contact lens–related infections,3 carry a similar risk.