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July 18, 2012

Retinal Detachment and Fluoroquinolones

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Department of Microbiology, Royal Free Hospital NHS Foundation Trust, London, England (Dr Molloy); and Department of Public Health Sciences, University of Edinburgh, Edinburgh, Scotland (Dr Mitry; mitryd@gmail.com).

JAMA. 2012;308(3):233. doi:10.1001/jama.2012.6620

To the Editor: A robust association between current fluoroquinolone use and retinal detachment was reported by Dr Etminan and colleagues.1 They stated that a group of residual confounders would need to be excessively large to change the results of the study. However, the cumulative effect of several important factors may account for, at least in part, the reported association.