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July 18, 2012

Supplementary Imaging for Breast Cancer Screening in High-Risk Women

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliation: Women's College Research Institute, Toronto, Ontario, Canada (steven.narod@wchospital.ca).

JAMA. 2012;308(3):236. doi:10.1001/jama.2012.7547

To the Editor: One objective of the recent study by Dr Berg and colleagues1 was to evaluate the potential for screening using MRI to identify breast cancers that were missed by a combination of ultrasound and mammography. After 3 rounds of screening by ultrasound and mammography, 612 women went on to have an MRI. In the 2662 women who received a mammogram and ultrasound, there were 111 breast cancers detected (4.2%), 91 by mammogram, ultrasound, or both. In the 612 women who later had an MRI, 16 cancers (2.6%) were detected.