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October 10, 2012

Postherpetic Neuralgia After Herpes Zoster Vaccination—Reply

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Department of Epidemiology, University of Alabama, Birmingham (jcurtis@uab.edu).

JAMA. 2012;308(14):1427-1428. doi:10.1001/jama.2012.12739

In Reply: We agree with Dr Lambert that it is of interest to examine the association between herpes zoster vaccination and the incidence of postherpetic neuralgia. Currently, there is no validated algorithm for identifying incident postherpetic neuralgia cases using administrative data, on which our study was based. In light of the inquiry from Lambert, however, we compared the estimated incidence rate of postherpetic neuralgia between vaccinated and unvaccinated patients.