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December 15, 1962

Resistant Gonococci

Author Affiliations

USAF, MC, 811th Medical Group, Loring AFB, Me.

JAMA. 1962;182(11):1137. doi:10.1001/jama.1962.03050500069021

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To the Editor:—  I have read with interest Dr. Schwimmer's reply to a question regarding antibiotic resistant gonococci in the Questions and Answers section of The Journal (179:586 [Feb. 17] 1962). However, many, if not all, apparent cases of gonococcal infection which will not respond to adequate penicillin actually are caused by bacteria of the tribe Mimeae, and not by the gonococcus at all. The tribe Mimeae comprises 3 known varieties: Mimeae polymorpha, Herela vaginicola, and Colloides anoxydana. These organisms appear on direct gram-stain smears or on bloodagar culture as gram-negative diplococci, both intra- and extracellular in location, and as such, are indistinguishable from the gonococcus. However, if cultured on MacConkey's enteric culture medium, the gonococcus will not grow, whereas the Mimeae will thrive. On sheep-blood agar the Mimeae will grow as gram-negative rods, while the Neisseria will be seen as the characteristic gram-negative diplococci. The tribe Mimeae causes