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Health Agencies Update
November 28, 2012

Drugs and Liver Injury

JAMA. 2012;308(20):2073. doi:10.1001/jama.2012.76683

Clinicians trying to pinpoint the cause of liver injury associated with the use of prescription or over-the-counter medications, herbal products, and dietary supplements may find help in the free LiverTox database created by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Library of Medicine.

Drug-induced liver injury accounts for about half of all cases of liver failure in the United States and primarily affects elderly individuals, who often take multiple medications or other products, according to the NIDDK. Finding out what substance is causing the injury is key to managing this condition, but this can be challenging.