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Lab Reports
December 12, 2012

Eradicating C difficile

JAMA. 2012;308(22):2326. doi:10.1001/jama.2012.111751

A combination of 6 naturally occurring bacteria can eradicate a highly contagious form of Clostridium difficile in mice (Lawley TD et al. PLoS Pathog. 2012;8[10]:e1002995). The mix included 3 previously described species (Staphylococcus warneri, Enterococcus hirae, and Lactobacillus reuteri) and 3 novel species.

Mice in the study were infected with a persistent form of C difficile that consistently relapsed to a high level of shedding or contagiousness after the animals were treated with a range of antibiotics.