[Skip to Content]
[Skip to Content Landing]
Views 1,222
Citations 0
February 13, 2013

Chloride-Restrictive Fluid Administration and Incidence of Acute Kidney Injury

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Department of Intensive Care Medicine, VU University Medical Center, Amsterdam, the Netherlands (Dr Elbers; p.elbers@vumc.nl); Department of Intensive Care Medicine, Herlev Hospital, Herlev, Denmark (Dr Gatz); and Department of Intensive Care Medicine, Sunshine Coast Hospital, Nambour, Australia (Dr Anstey).

JAMA. 2013;309(6):542-543. doi:10.1001/jama.2012.171511

To the Editor: In a study showing an association between a chloride-liberal fluid administration and kidney injury in critically ill adults, Dr Yunos and colleagues1 acknowledged the potential problems of their study not being blinded or randomized. Nevertheless, we agree that the results justify prudence in prescribing chloride-liberal fluids in this population, especially because alternatives such as lactated Ringer solution are inexpensive and readily available.