To the Editor: Dr Gaziano and colleagues1 reported results from a large-scale, randomized, double-blind, placebo-controlled trial showing daily multivitamin supplementation modestly but significantly reduced the risk of total cancer. Although we agree that these data provide support for the potential use of multivitamin supplements in the prevention of cancer in middle-aged and older men, we have several comments with respect to the data.
Wang Z, Ji Y, Li Z. Multivitamins for Cancer Prevention in Men. JAMA. 2013;309(10):980. doi:10.1001/jama.2013.1188
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