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Lab Reports
April 3, 2013

Good vs Bad Bacteria in the Gut

JAMA. 2013;309(13):1337. doi:10.1001/jama.2013.2592

Introducing normal anaerobic bacteria into the gut largely eliminates vancomycin-resistant bacteria from the intestinal tracts of mice, suggests new research from Memorial Sloan-Kettering Cancer Center, in New York, and Centro Superior de Investigación en Salud Pública, in Valencia, Spain (Ubeda C et al. Infect Immun. 2013;81[3]:965-973).

The study involved giving antibiotic-treated mice fecal transplants from untreated mice or cultures from the fecal transplants. Although treatment with the aerobic culture was ineffective at eliminating antibiotic-resistant bacteria, treatment with the fecal transplant or the anaerobic culture led to a billion-fold reduction in the density of intestinal vancomycin-resistant bacteria.