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Global Health
June 19, 2013

Weaning Affects HIV Levels in Breast Milk

JAMA. 2013;309(23):2430. doi:10.1001/jama.2013.7390

Changes in breastfeeding routines during the time of weaning influence the concentration of HIV in breast milk, according to findings from a randomized clinical trial in Zambia (Kuhn L et al. Sci Transl Med. 2013;5[181]:181ra51).

Researchers from the United States and Zambia tested different breastfeeding routines during a 24-month period in 958 women infected with HIV. All women were counseled to breastfeed for 4 months, at which point half were encouraged to wean abruptly while the other half continued breastfeeding as long as they chose to do so. HIV-1 RNA and DNA were measured at 4 and 4.5 months.