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June 26, 2013

Fibrosis and Mortality in Patients With Dilated Cardiomyopathy

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Departments of Epidemiology (Dr Leening) and Public Health (Dr Steyerberg), Erasmus University Medical Center, Rotterdam, the Netherlands (m.leening@erasmusmc.nl).

JAMA. 2013;309(24):2547-2549. doi:10.1001/jama.2013.6470

To the Editor: Dr Gulati and colleagues1 examined whether information about the presence of myocardial fibrosis aided in the prediction of mortality and major arrhythmia in 472 patients with nonischemic dilated cardiomyopathy. The predictive ability of fibrosis over left ventricular ejection fraction was quantified using the net reclassification improvement (NRI) index.2