A protein produced within the brain acts like antiepileptic drugs, report researchers from Stanford University School of Medicine in Stanford, California (Christian CA et al. Neuron. doi:10.1016/j.neuron.2013.04.026 [published online May 30, 2013]). In addition to being an intracellular transporter of a metabolite called acyl-CoA, the protein, diazepam binding inhibitor (DBI), binds to receptors on nerve cells that are responsive to the inhibitory neurotransmitter γ-aminobutyric acid type A (GABAA).
Hampton T. Brain Protein May Suggest New Epilepsy Treatment Strategy. JAMA. 2013;310(1):22. doi:10.1001/jama.2013.7873
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: