In Reply Dr Ji and colleagues suggest that other changes in behavior associated with smoking cessation, such as change in diet and decrease in alcohol consumption, might contribute to the decrease in cardiovascular disease we observed in our study. We agree that smokers might adopt a healthier lifestyle when they quit smoking.
In the Comment section of our article, we cited this as one of the mechanisms for a decrease in cardiovascular disease associated with smoking cessation. However, the main objective of our study was not to explore potential mechanisms responsible for the decrease in cardiovascular risk when smokers quit smoking but to test the hypothesis that weight gain following smoking cessation does not attenuate the cardiovascular benefits of smoking cessation.
Clair C, Rigotti NA, Meigs JB. Smoking Cessation, Weight Change, and Risk of Cardiovascular Disease—Reply. JAMA. 2013;310(3):323. doi:https://doi.org/10.1001/jama.2013.7945
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