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Comment & Response
July 17, 2013

Long-term Follow-up of Young Adults With Stroke—Reply

Author Affiliations
  • 1Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
JAMA. 2013;310(3):321-322. doi:10.1001/jama.2013.7948

In Reply Drs Vidale and Bono and Dr Sciascia and colleagues suggest that the factors responsible for the high long-term mortality after stroke in young adults should be investigated. However, the aim of our study was to provide estimates of mortality for selected subgroups of stroke (transient ischemic attack, ischemic stroke, and intracerebral hemorrhage). High-risk groups within this population can be identified.

One of the factors that Vidale and Bono propose is clinical severity and disability. However, a previous study1 did not find an association between stroke severity and 5-year mortality after stroke in young adults, whereas another study2 showed an association between stroke severity and a combination of unfavorable outcome and death within 3 months after stroke in young adults.