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My chief purpose in reviewing the subject of hay fever is to define more clearly, if possible, the philosophy of its treatment by internal medication in addition to the recognized surgical measures which should be adopted. The majority of patients have received only local nasal treatments, which have given variable success, no effort being made at internal medication. My experience in the past three seasons has convinced me that one of the most important factors in the pathology of the disease is the uric acid diathesis, or rather a condition of temporary uricacidemia. Uric acid, with other toxic matters which are retained with it in the blood, is certainly a violent irritant to the tender and irritable tissues in hay fever as well as in other diseased states; and when its importance is fully recognized it will be much easier to relieve the sufferer.
The nervous symptoms are reflex, from
WEAVER WH. HAY FEVER. JAMA. 1898;XXX(23):1334–1336. doi:10.1001/jama.1898.72440750022002g
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