Since the discovery of the embryos of Filaria nocturna in the peripheral circulation by Lewis, in 1872, very few observers have devoted their attention to the changes in the blood associated with this disease.
In 1894 Bancroft and Bancroft1 noted a leucocytosis in filariasis and published the following blood counts, no differential blood counts being made:
Lothrop and Pratt,2 in 1900, found the whites in two cases to be about normal; their highest count was 8,000, lowest 3,500. Differential counts showed 4.6 and 3.5 per cent, of eosinophiles.
G. L. Gullard3 found a leucocytosis varying from 4,600 to 13,500, and an eosinophilia varying from 3 to 12 per cent. He observed the highest leucocytosis and eosinophilia when the number of embryos in the peripheral circulation was greatest; and a decrease in the leucocytes and eosinophilia accompanying the decrease of the embryos in the peripheral circulation.
CALVERT WJ. THE BLOOD IN FILARIASIS. JAMA. 1902;XXXIX(24):1523–1525. doi:10.1001/jama.1902.52480500029002e
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