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November 17, 1962

Regional Notes

JAMA. 1962;182(7):56-57. doi:10.1001/jama.1962.03050460128029

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Abstract

Cincinnati Pharmacologist Tells of Phocomelia Study  A German-born pharmacologist at the University of Cincinnati, Dr. Gunter Grupp, has released a report on a survey he made in August and September of the birth defect epidemic in Germany.Grupp, associate professor of experimental medicine and pharmacology, visited medical centers in nine cities in north Germany and five in south Germany. He said that in all places where the patients had been carefully studied, "there were always more than 25% in which thalidomide could not be found in the history."Some experts in Germany, he said, believe these "negative cases" must have taken the drug unknowingly; others think the number of such cases shows that thalidomide is not the only cause of such malformations in the newborn. Grupp said that at present there is no proof of thalidomide being the only responsible agent.The Cincinnati researcher asked five German physicians who have

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