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Current Concepts in Cancer—NO 2
January 4, 1965

Radiation Therapy

JAMA. 1965;191(1):28-29. doi:10.1001/jama.1965.03080010034008

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This's in 1832 until quite recently was associated with a fatal prognosis. For several decades there have been occasional reports of cures and long-term survivors of isolated cases of Hodgkin's disease treated by surgery or radiotherapy, but because of the rarity of the disease a true perspective of its various patterns of progress was difficult to obtain. With the advent of "centralization" of cancer treatment, it became possible to concentrate a sufficient number of case histories to allow analyses. Consequently it is now possible to identify patients with Hodgkin's disease who have a more favorable prognosis.

The first representative analysis reported by this author7 in 1950 suggested a purely clinical classification which has since been modified in various ways and by other analysts. The sample staging employed for the most recent analysis8 from this Institute is as follows:

Stage I. Involvement of a single site or lymphatic region.