During closed-chest cardiac massage, left-atrial and systemic arterial blood pressures are nearly equal. The former falls while the latter rises toward prearrest values with the resumption of effective cardiac activity. The high left-atrial pressures may explain pulmonary edema after prolonged closed-chest cardiac massage. An extremely critical state exists as long as there is no effective cardiac contraction even if a satisfactory systemic arterial blood pressure is maintained by closed-chest cardiac massage.
Thomsen JE, Stenlund RR, Rowe GG. Intracardiac Pressures During Closed-Chest Cardiac Massage. JAMA. 1968;205(1):46–48. doi:10.1001/jama.1968.03140270070019
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