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To the Editor.—
Ross and colleagues have written a timely article on the neuropathological consequences associated with boxing. Their conclusions are, however, weakened by certain methodological difficulties.Although the authors emphasize that the CT scores they report are adjusted for normal, age-dependent changes in sulcal and ventricular size, multiple regression analysis of their data reveals that fighter age remains the most significant correlate of observed CT scan abnormalities (R=.409, P<.02). In addition, multiple regression analysis fails to show a significant correlation of CT scores with the number of bouts fought (R=.239, P>.05). Statistical data are summarized in Tables 1 and 2.While these results conflict with the conclusions drawn by the authors, they point out an interesting possibility. Could the normal CT scan changes that occur with age be accelerated in some way by boxing? By including age-matched, normal controls and reporting the CT scan changes
Naviaux RK. Boxing. JAMA. 1983;249(20):2777–2778. doi:10.1001/jama.1983.03330440017011
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