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Comment & Response
August 7, 2013

BRAF V600E Mutation and Papillary Thyroid Cancer

Author Affiliations
  • 1Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland
JAMA. 2013;310(5):535. doi:10.1001/jama.2013.8592

To the Editor Our recent multicenter study1 reported an association between BRAF V600E and PTC-related patient mortality. However, this association was not independent of tumor behaviors and the prognostic value of BRAF V600E was debated in an accompanying Editorial.2 This issue warrants further discussion in several aspects.