To the Editor: We are concerned about aspects of the study design in the article on racial differences in BRCA1/2 testing by Dr Armstrong and colleagues, and believe that the results should be interpreted with caution.1 In a case-control study, controls should be sampled from the population that gave rise to the cases.2,3 However, the description of this study leaves questions about whether appropriate sampling has occurred.
Alford SH, Mouchawar J. Racial Differences in BRCA Testing. JAMA. 2005;294(6):677. doi:https://doi.org/10.1001/jama.294.6.677-a
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