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Medical News & Perspectives
September 25, 2013

Low Diastolic Blood Pressure and Chronic Kidney Disease Are Associated With Increased Mortality

JAMA. 2013;310(12):1215-1216. doi:10.1001/jama.2013.277706

When treating hypertension, physicians, patients, and clinical guidelines focus on reducing systolic blood pressure. Diastolic blood pressure tends to be a secondary concern, as it usually decreases when systolic pressure is reduced.

But when diastolic pressure is too low—in general, less than 70 mm Hg—it is associated with increased cardiovascular events (including mortality), especially in older patients and those with established coronary artery disease and diabetes. Now, a new study adds chronic kidney disease to the list of conditions that appear to be adversely affected by low diastolic pressure (Kovesdy CP et al. Ann Intern Med. 2013;159[4]:233-242).