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Medical News & Perspectives
October 2, 2013

Malaria Vaccine, Ebola Therapy Promising in Early Studies

JAMA. 2013;310(13):1327-1328. doi:10.1001/jama.2013.278188

After years of work on efforts to control 2 major tropical diseases, researchers have reported important developments that may lead to a malaria vaccine and a treatment for Ebola virus infection.

One team of researchers demonstrated in a small, preliminary trial that intravenous injections of purified cryopreserved Plasmodium falciparum sporozoites can successfully protect individuals against malaria infection. A second group found in a small study in rhesus macaques that a cocktail of monoclonal antibodies derived from plants may substantially reduce the risk of death from Ebola, even after clinical symptoms appear.