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Comment & Response
December 11, 2013

Therapy for Posttraumatic Stress and Alcohol Dependence—Reply

Author Affiliations
  • 1Center for the Treatment and Study of Anxiety, University of Pennsylvania, Philadelphia
JAMA. 2013;310(22):2458-2459. doi:10.1001/jama.2013.282158

In Reply Dr Najavits states that our findings would be interpreted differently if considered from a public health perspective, noting that results of this trial were null for prolonged exposure therapy. In truth, our results showed that prolonged exposure therapy, especially when combined with naltrexone, significantly reduced alcohol craving and alcohol relapse, findings that are relevant to public health. In addition, a significantly greater proportion of patients who received prolonged exposure therapy (vs those who did not) had minimal PTSD symptoms 6 months after treatment discontinuation.