Metabolic Responses to Reduced Daily Steps in Healthy Nonexercising Men

To the Editor: Increased daily physical activity is associated with improved health,¹ but it is uncertain whether it prevents initial metabolic events that produce chronic diseases. We are aware of no evidence in healthy, young adults that reduced daily stepping within a free-living environment is associated with negative metabolic consequences. The purpose of this study was to reduce daily steps and assess metabolic changes.