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The World in Medicine
March 19, 2008

Prostate Cancer Genes

JAMA. 2008;299(11):1252. doi:10.1001/jama.299.11.1252-b

Three independent groups of scientists from Europe and the United States have identified at least 10 previously unknown gene variants linked to prostate cancer susceptibility, according to findings reported online ahead of print on February 10 (Eeles RA et al. Nat Genet. doi:10.1038/ng.90; Thomas G et al. Nat Genet. doi:10.1038/ng.91; Gudmundsson J et al. Nat Genedoi:10.1038/ng.89).

Each of the groups conducted genome-wide association studies of thousands of individuals with and without prostate cancer. All told, 10 gene loci on chromosomes 2, 3, 6, 7, 10, and 11 and the X chromosome were found.