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May 28, 2008

Adverse Events Associated With Stopping Clopidogrel After Acute Coronary Syndrome

JAMA. 2008;299(20):2388-2390. doi:10.1001/jama.299.20.jlt0528-g

To the Editor: In their study of death and acute myocardial infarction after stopping clopidogrel, Dr Ho and colleagues1 concluded that there is significant thrombotic risk with increased rates of death and acute myocardial infarction in the immediate period after stopping clopidogrel. However, there are 2 pieces of information not provided in the article that could affect the validity of the conclusions.