High blood pressure (BP) is a well-documented risk factor for cardiovascular disease (CVD) and chronic kidney disease progression.1,2 These associations, however, are based on BP measured at a single time point in middle- or older-aged persons.3 Consequently, traditional CVD risk prediction models4 consider BP level only at the time of risk prediction and ignore cumulative BP levels over time. This is also true for the majority of outcome trials used to form clinical practice guidelines.5
Sarafidis PA, Bakris GL. Early Patterns of Blood Pressure Change and Future Coronary Atherosclerosis. JAMA. 2014;311(5):471–472. doi:10.1001/jama.2013.285123
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