One of the most contentious topics in public policy debates on genetics has been the use of genetic information by insurance companies. In the rush to confront concerns about potential misuses of genetic information, most European countries have since 1990 enacted genetic nondiscrimination legislation for life or health insurance. In the United States, the Genetic Information Nondiscrimination Act (GINA) was recently signed into law to provide protection against genetic discrimination for employment and health insurance.1,2