In Reply: Dr Balamuthusamy and colleagues question the clinical relevance of asymptomatic thrombotic events. These events did not influence catheter removal in our study because ultrasound evaluations were performed after catheter removal. Review of severe adverse events in the participants identified no case of fatal pulmonary embolism related to the studied catheter. Because critically ill patients included in our study did not undergo systematic pulmonary evaluation or autopsy, I cannot comment further on the risk of pulmonary embolism; however, this topic is discussed in a study by Timsit et al.1
Parienti J. Femoral vs Jugular Venous Catheterization for Short-term Dialysis Access—Reply. JAMA. 2008;300(15):1760–1761. doi:10.1001/jama.300.15.1761-b
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