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Comment & Response
February 12, 2014

Acute Muscle Wasting Among Critically Ill Patients

Author Affiliations
  • 1Clinical Evaluation Research Unit, Kingston, Ontario, Canada
  • 2Department of Food Science and Nutrition, University of Minnesota, Minneapolis
  • 3University of Pennsylvania School of Nursing, Philadelphia
JAMA. 2014;311(6):621-622. doi:10.1001/jama.2013.285420

To the Editor The prospective study by Dr Puthucheary and colleagues1 characterized acute muscle wasting in patients with critical illness. We take exception to the clinical inference that protein delivery was associated with increased muscle wasting. These findings conflict with existing data that higher protein delivery is associated with improved survival, reduced infection, and improved health-related quality of life.2,3