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Comment & Response
February 12, 2014

Fetal Outcomes Associated With Metoclopramide Use in Pregnancy—Reply

Author Affiliations
  • 1Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
JAMA. 2014;311(6):624. doi:10.1001/jama.2013.285289

In Reply Dr Vrachnis and colleagues claim that our study does not account for dosage with sufficient detail. We do not agree.

First, they state that dosage was not reported in the article. However, the number of dispensed doses was reported as a median of 40 doses (interquartile range, 30-40 doses). The number of dispensed doses corresponds to units of the drug, which in Denmark includes tablets containing 10 mg and suppositories containing 20 mg, 2 formulations of metoclopramide that are considered equipotent.