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February 25, 2009

Mild Cognitive Impairment, Carotid Disease, and Revascularization

JAMA. 2009;301(8):829-830. doi:10.1001/jama.2009.172

To the Editor: In his Clinical Crossroads article about Ms E, a 60-year-old woman with mild memory impairment, Dr Ellison indicated that “it is reasonable . . . to obtain carotid ultrasound studies to determine whether blood flow is compromised to the point of requiring intervention for stroke prevention.”1 Although Ms E has stroke risk factors, white matter disease, and an upgoing toe, she was not reported to have had a clinical event consistent with stroke or transient ischemic attack (TIA). Therefore, even if she had significant carotid stenosis, the stenosis would not be considered symptomatic, and revascularization therapy would not be indicated.