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The World in Medicine
January 14, 1998

Cholesterol Blocker

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JAMA. 1998;279(2):101. doi:10.1001/jama.279.2.101-JWM71007-2-1

Alongside the statin drugs used to lower serum cholesterol comes an agent with new therapeutic potential: margarine.

In the December 16 Circulation, researchers from the University of Helsinki in Finland reported that margarine containing sitostanol ester effectively blocked cholesterol absorption and reduced levels of serum cholesterol and low-density lipoprotein (LDL) cholesterol in a group of postmenopausal women with previous myocardial infarction.