To the Editor: In their study of outcomes in adults with bicuspid aortic valves, Dr Tzemos and colleagues1 concluded that age, severity of aortic stenosis, and severity of aortic regurgitation were independently associated with primary cardiac events. Identification of outcome predictors that could help in the selection of patients who are likely to benefit from intervention such as surgery would be highly desirable.
Song Z. Valve Calcification and Patients With Bicuspid Aortic Valves. JAMA. 2009;301(9):935–936. doi:10.1001/jama.2009.118