Author Affiliations: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Dr McDermott); and Department of Family and Preventive Medicine, and Department of Medicine, University of California, San Diego School of Medicine, San Diego (Dr Criqui). Dr McDermott is a Contributing Editor, JAMA.
Lower extremity peripheral artery disease (PAD) is common among older men and women in developed countries and will become increasingly prevalent as populations survive longer with chronic disease. Recent estimates in the United States indicate that 1 in 16 men and women 40 years or older have PAD.1 In primary care medical practices in the United States, nearly 30% of men and women who are either 70 years or older or aged 50 to 69 years with a history of diabetes or smoking have an ankle-brachial index (ABI) of less than 0.90, consistent with PAD.2
McDermott MM, Criqui MH. Aspirin and Secondary Prevention in Peripheral Artery Disease: A Perspective for the Early 21st Century. JAMA. 2009;301(18):1927–1928. doi:10.1001/jama.2009.668
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