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Books, Journals, New Media
July 1, 1998

Helicobacter: Helicobacter

Author Affiliations

Harriet S.MeyerMD, Contributing EditorJonathan D.EldredgeMLS, PhD, Journal Review EditorRobertHoganMD, adviser for new media


Not Available

JAMA. 1998;280(1):100. doi:10.1001/jama.280.1.100-JBK0701-4-1

Why devote an entire journal to such a narrow subject—a bacterium that until a few years ago was considered fairly unremarkable? Helicobacter pylori infections are a worldwide health problem. In the United States approximately 25% of the general population harbors this bacterium. Incidence increases with age, and prevalence is high in the less industrialized areas of the world, where more than 70% of the older population are infected.1 As a result of infection, up to 10% of the population of the United States will have peptic ulcer disease, and a small but significant percent will develop gastric malignancy. The mode of transmission and mechanism and extent of pathogenicity related to subtype, as well as the therapeutic approach, continue to require further elucidation.