A genetic trait associated with Alzheimer disease has been linked to an increased risk of osteoporotic fractures.
In a new study, researchers at the University of Pittsburgh and the University of California at San Francisco reported that older women with a form of the gene for apolipoprotein E (APOE) have a substantially increased risk of hip and wrist fractures. The researchers followed 1750 women aged 65 years and older for 7 years. They evaluated bone mineral density, APOE gene alleles, cognitive function, and the occurrence of wrist and hip fractures and falls in the study participants.
Voelker R. Gene Influences Fractures. JAMA. 1999;282(4):317. doi:10.1001/jama.282.4.317-JQU90005-3-1
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: