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Medical News & Perspectives
August 18, 1999

Mild Cognitive Impairment Raises Alzheimer Disease Risk

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JAMA. 1999;282(7):621-622. doi:10.1001/jama.282.7.621-JMN0818-2-1

Chicago—As therapeutic strategies for Alzheimer disease (AD) begin to emerge, interest has focused on identifying signs of mental decline as early as possible to prevent, delay, or reverse disease-associated brain damage. Experts in the field say a condition known as mild cognitive impairment (MCI), which precedes development of AD and other dementias in many people, appears to be a signal of disease onset that will help target individuals for early interventions.