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The World in Medicine
January 9, 2002

Malaria Vaccine Studies

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JAMA. 2002;287(2):180. doi:10.1001/jama.287.2.180-JWM10014-3-1

An experimental malaria vaccine offers partial protection against Plasmodium falciparum infection, according to a report by investigators from Gambia, the United Kingdom, the United States, and Belgium (Lancet. 2001;358:1927-1934).

In the randomized trial, which took place in Gambia at the beginning of the malaria season, 250 men received three doses of the malaria vaccine or a control inoculation with rabies vaccine. Over the next 15 weeks, men who received the rabies vaccine became infected more quickly than those who received the malaria vaccine.